Pharma - R + {rtables}: Tables

2020-12-23

When working for Roche, I was involved in NEST, a project developing a set of tools for the production of tables, figures and listings meeting pharma requirements. The package rtables, developed at Roche by Gabriel Becker & Adrian Waddell, was the corner stone for the tables offering an appealing framework:

With this simple readable code:

basic_table() %>% 
  split_cols_by(var = "ARMCD") %>%
  add_colcounts() %>%
  analyze(c("AGE", "SEX"), s_summary) %>%
  build_table(ADSL) 

You could get:

                      A: Drug X     B: Placebo    C: Combination
----------------------------------------------------------------
AGE                                                             
  n                      134            134            132      
  Mean (sd)          33.77 (6.55)   35.43 (7.9)    35.43 (7.72) 
  IQR                     11            10              10      
  min - max            21 - 50        21 - 62        20 - 69    
SEX                                                             
  F                       79            77              66      
  M                       51            55              60      
  U                       3              2              4       
  UNDIFFERENTIATED        1              0              2       

A Not So Short Introduction to rtables (by Gabriel Becker & Adrian Waddell, 2020) is available as a GitHub page; it was proposed at the 2020 RStudio Table Contest.

@Manual{,
    title = {rtables: Reporting Tables},
    author = {Gabriel Becker and Adrian Waddell},
    year = {2021},
    note = {R package version 0.3.6},
    url = {https://CRAN.R-project.org/package=rtables},
}